c-LEcta GmbH was established in September 2004 as a spin-off from the University of Leipzig. To date, c-LEcta has shaped into a leading industrial biotech company and provides customized, best-in-class enzymes and microbial strains for the production of high value industrial products. c-LEcta constantly improves its own proprietary technologies and processes and supports industrial partners in both new and existing markets. The knowledge and expertise of over 50 employees in the discovery, optimization and production of enzymes, as well as engineering of diverse microbial strains, has led to more than 5 successfully launched products in collaboration with top tier industry partners. c-LEcta’s contribution to cost-efficient and sustainable production processes are of great importance to currently regulated industrial sectors like pharma and food.

The company has developed several proprietary methods for the identification of new enzymes from natural biodiversity, the optimization of enzymes for industrial processes, and the development of efficient enzyme production processes. c-LEcta's enzyme development platform has evolved over the past 10 years, following the primary objective of fast access to the optimal biocatalysts in a streamlined manner. The platform consists of unique and proprietary methods like cluster screening, c-LEcta mutagenesis and bioinformatics tools. Methods are regarded as both reliable and high in quality, thus resulting in excellent hit rates in enzyme libraries and speed of enzyme development projects. The success of c-LEcta’s enzyme engineering platform has been demonstrated over the last 10 years for various enzyme classes and engineering objectives.

c-LEcta's key contributions to the ShikiFactory100 project include: development of a structural bioinformatics platform for gene selection and enzyme engineering, and the implementation of low/medium throughput enzyme engineering methods. They are important contributors to Work Package 4: Gene Discovery and Protein Engineering.

The Principal Investigator for c-LEcta in the ShikiFactory100 project is Dr Andreas Vogel.

Find out more about c-LEcta here.